HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer. While indispensable for embryonic patterning ...

While anticancer treatments, including many forms of chemotherapy and radiation, can effectively kill cancer cells, long-term use can cause mutations in healthy cells. Mutations arising in cells that ...

For the first time, a team of experts from the Technical University of Munich (TUM), RWTH Aachen University, and the German ...

A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...

In recent years, cancer immunotherapy has transformed the treatment landscape for a wide range of malignancies, offering ...

Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells. However, many cancers can ...

Much of pancreatic cancer’s evasive and deadly nature may come down to low levels of one gene. In A Nutshell Early detection, ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...