The regulation of the cell cycle is a fundamental process ensuring the accurate replication and division of cells. Central to this regulation are the Cdc25 phosphatases, which activate ...
Ubiquitination is a crucial post-translational modification process where the small protein ubiquitin is attached to target proteins, marking them for degradation or altering their function. This ...
The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...
Understanding why cancer cells rely on specific genes is critical for designing effective targeted therapies. A new study systematically maps the molecular dependencies of breast cancer cells by ...
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Super-enhancers: Cancer's double-edged sword of growth and DNA damage
New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...
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