How is it that your body with all of its specialized organs developed from a single cell? Scientists are exploring how gene expression patterns and their timing regulate cell differentiation. Today, ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Metabolic diseases such as obesity, fatty liver, and insulin resistance are rapidly increasing worldwide, but fundamental ...

Researchers at the CiRA Foundation in Kyoto, Japan, have published a detailed study [1] showing how carefully defined culture ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining the ...

In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one ...