As rare disease trials face persistent feasibility challenges, Bayesian designs are gaining momentum by enabling more ...

When Elise Felicione tried to design a clinical trial for a supplement, 5 things got in the way. It’s a lesson for the ...

UniQure faces a setback as the FDA demands a placebo-controlled study for its Huntington's gene therapy, rejecting the recent ...

However, traditional clinical trial designs are often ill-suited for rare disease research with common challenges including ...

Despite a trend toward more patient-centered research, quality-of-life end points remain substantially underreported in phase ...

“Well, we don’t have as much evidence as we would like on steroid use during pregnancy,” the obstetrician warned my co-author, Natalia Emanuel, as she wrote a prescription for inhaled corticosteroids ...

A major challenge in the clinical trial space is ensuring a diverse group of patients enrolls in the program. | A major challenge in the clinical trial space is ensuring a diverse group of patients ...

A 5-day amoxicillin challenge was feasible for evaluating delayed penicillin allergy, with more than 80% of participants ...

The GoGoVax randomized controlled trial found that 4CMenB does not reduce gonorrhoea incidence in high-risk gay and bisexual ...