Acetylcholine "conductors" in the striatum directly trigger serotonin release, offering new insights into the origins of OCD and chemical imbalances.

Researchers have identified a mechanism by which acetylcholine, a neurotransmitter best known for its role in muscle control and attention, can effectively commandeer serotonin release inside the ...

Due, in part, to the logical nature of the approach, combination therapy is already widely used in clinical practice. Although compounds with a combined cholinergic–glutamatergic action have been ...

Kaiser Permanente Washington scientists report that higher cumulative anticholinergic exposure predicted a faster decline in gait speed and grip strength among older adults. Inappropriate polypharmacy ...

Expert Rev Neurother. 2012;12(11):1351-1365. With regard to understanding the disease process in AD, it is of considerable interest to consider the temporal relationship between the loss of ...