Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

It’s hard to improve on a classic. But Richard Y. Liu was eager to take on that challenge. Cross-coupling reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, are some of the ...

Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly, a molecule makes a promising new medicine. Normally, creating better ...

Researchers develop a one pot process to transform aromatic ketones to esters, offering advancements in pharmaceutical synthesis and materials science. Aromatic ketones have traditionally been ...

A new catalyst strategy developed at Institute of Science Tokyo uses BaSi2 as a support for nickel and cobalt to decompose ...

Recently, the National Science Review published the research outcome from Prof. Jun Cheng (Xiamen University) and Dr. Jia-Bo Le (Ningbo Institute of Materials Technology and Engineering of Chinese ...

Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...

A straightforward and reproducible synthesis pathway for a diverse range of ATP- and ADP-coupled biomolecules has been developed by modifying an established reagent. Researchers at the Institute for ...

An illustration of a person in a lab coat looking at a picket fence. The field is various elements, metals specifically. Credit: Chris Gash On a summer day about 20 years ago, Paul Chirik returned to ...