Notably, the paper also includes simulation studies outlining when dDRTC is most effective, positioning it as a practical ...

The discovery of a stable single-electron covalent bond between two carbon atoms validates a century-old theory. The discovery of a stable single-electron covalent bond between two carbon atoms ...

Covalent inhibitors are a specialized class of small molecules designed to form chemical bonds with their target proteins, often resulting in prolonged target engagement and enhanced potency. The ...

Scientists mapped where drugs bind inside the body, cell by cell, to better understand benefits and side effects.

Halogen bonds were first proposed as an activating interaction in 2008, but this alternative type of organocatalysis was ...

Researchers have found a new type of cross-link between amino acids in a protein (Nature 2021, DOI: 10.1038/s41586-021-03513-3). The intramolecular linkage is an N-O-S bridge formed by oxidizing the ...