During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.
Diffuse midline glioma (DMG), H3K27-altered, is a lethal pediatric high-grade tumor, lacking effective treatment options, primarily depending on clinical trials. Epigenetic agent-based immunotherapy ...
Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...
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Reprogramming the epigenetic code affects growth and survival of tumor cells in multiple myeloma
In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of chemical "tags" on DNA and proteins that control whether genes are turned on or ...
Metabolic diseases such as obesity, fatty liver, and insulin resistance are rapidly increasing worldwide, but fundamental methods to regulate the process of fat formation remain limited. In particular ...
Researchers at Karolinska Institutet have discovered how cells can adjust their gene activity to survive when oxygen runs low. The study, published in Nature Cell Biology, reveals that cells use a ...
Market expansion in med derm cross over: Almirall’s Seysara (sarecycline) won NMPA approval for moderate to severe acne (≥9 years), with China commercial launch targeted for 2026 – relevant to ...
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