The genetic information stored in DNA is a living archive of instructions that cells use to accomplish the functions of life. Inside each cell, catalysts seek out the appropriate information from this ...

Bacterial ribosomes are central to protein synthesis, and their regulation is vital for adaptation to environmental stresses. Under conditions such as nutrient deprivation, cold shock or hypoxia, ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Proteins are absolutely essential for the survival of organisms; they carry out many functions that are critical to life. Something needs to build all of those proteins from their basic components.

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...

New studies shed light on how mRNAs are born and how they regulate production of proteins inside of our cells once they reach maturity. The findings have implications not only for achieving effective ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. They are characterized by tissue-specific phenotypic abnormalities that consequently increase ...

Led by Northwestern Engineering’s Michael Jewett, researchers created a new version of an engineered tethered ribosome dubbed Ribo-T, which provides a foundation to propel broad, new efforts in ...

Vaccinations have revolutionized healthcare, but designing them remains complex, requiring time and creativity, especially for vaccines against viruses, which are difficult to study. “Each virus ...

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...