In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

One problem in gene therapy is that not all genes transfer equally well into the target cells. Researchers have now developed a flexible method to transfer large genes efficiently and without ...

Research is shaking up how we think about evolution, suggesting there's a level of predictability influenced by genes and genetic history.

The ability to control the expression of therapeutic genes within a “therapeutic window” is crucial to ensure the development of safe and effective gene therapies, but to date, there has been no ...

Theodore Friedmann, professor of pediatrics at the University of California, San Diego, is also director of the Program in Gene Therapy there. The overriding interest of his laboratory is gene therapy ...