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Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

In 1997, Alan Leshner, then director of the National Institute for Drug Abuse, wrote an article entitled “Addiction Is a Brain Disease and It Matters.” That eight-word title became the perfect sound ...

One way to get that pleasure is to seek retaliation. Additional brain scan studies have shown that when people imagine ...

Methamphetamine doesn’t just spike levels of the pleasure-inducing hormone dopamine in the reward pathways of the brain – it ...

Much of the conversation around addiction swings between two worldviews. On one side is the belief that addiction is a brain disease, that the addicted person’s brain compels them to continuously use ...