IFLScience on MSN

There Could Be A Surprising Health Benefit To Having Gray Hair

Going gray is an inevitable, and for many, undesirable, part of aging, but health-wise, it’s no bad thing – it could reflect ...
Hosted on MSN

Reciprocal interaction between extrachromosomal DNA maintenance and DNA damage response revealed

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...

Rakovina Therapeutics Showcases Potent AI-Developed ATR Inhibitors with CNS Penetrance at AACR-NCI-EORTC International Conference

Through its collaboration with Variational AI, Rakovina Therapeutics utilized the Enki™ generative AI platform to identify novel small-molecule candidates predicted to meet a defined target product ...
Business Wire

Genialis Advances Biomarker Discovery to Reduce Risk in Cancer Drug Development Targeting DNA Damage Response Pathways

BOSTON--(BUSINESS WIRE)--Genialis, the RNA biomarker company, today announced an extension of its collaboration with Debiopharm, a Swiss-based global biopharmaceutical company, to develop a predictive ...
ascopubs.org

AlphaMissense for Identifying Pathogenic Missense Mutations in DNA Damage Repair Genes in Cancer

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...
Science Daily

Researchers identify DNA changes, biological pathways associated with inherited cancer risk

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk. Thousands of single ...
Labroots

Circulating Tumor DNA can Identify Mutations in Pancreatic Malignancies

Circulating tumor DNA (ctDNA), small pieces of DNA released from dying tumor cells into the bloodstream, can be easily and non-invasively identified and examined through a simple blood test. This ...
Nanowerk

Nanopore technique tracks DNA damage to aid cancer therapy and radiation response

Scientists developed a fast DNA damage test for radiation that could guide cancer care and help responders deliver personalized treatment during radiological emergencies. (Nanowerk News) Scientists at ...