IN 1948 and 1950 Lindblom 1,2 reported his experience with diskography. In these reports he described a method of direct visualization of normal and pathologic lumbar intervertebral disks by means of ...

Thus, the disk cells themselves can assume the functions of immune cells and can generate alarm signals, triggering the ...

This week we are going to discuss the intervertebral disc derangement of the lumbar spine. This is a very common and very painful condition which can affect both the back and/or leg. The ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, "Runx1 overexpression induces early onset of intervertebral disc degeneration." In this study, led by ...

The intervertebral discs between the spinal vertebrae comprise a gel-like core, the nucleus pulposus (NP), encased by a tough, fibrous outer ring. The NP’s high water content allows it to act like a ...

For decades, the intervertebral disc (IVD) has been framed in clinical and research narratives as a structure that inevitably degrades, a biomechanical victim of ageing and axial stress.1 This ...

A slipped disk can happen anywhere along the spine. Despite the name, the intervertebral disk does not slip out of place. Instead, the inner material protrudes through the disk’s outer ring, causing ...