SAN DIEGO, CA—In critically ill adult patients, extended infusion of meropenem correlates with a faster progression to death vs. intermittent infusion of the drug ...

Critically ill sepsis patients did not fare better with prolonged infusions of meropenem compared with intermittent infusions of the beta-lactam antibiotic, a randomized trial showed. Among over 600 ...

The use of intravenous antibiotics to treat patients at home requires that the therapy be provided safely and cost-effectively. Ideal agents for home use provide the necessary spectrum of ...

Tango I was a randomised, double-blind, double-dummy trial that compared meropenem with vaborbactam (2 g/2 g IV [intravenous] over 3 hours, every 8 hours) with piperacillin with tazobactam (4 g/0.5 g ...

Prolonged infusion of beta-lactam antibiotics for sepsis or septic shock tended to improve mortality compared with conventional intermittent infusion in the BLING III trial, and a meta-analysis ...

Please provide your email address to receive an email when new articles are posted on . When comparing continuous vs. intermittent infusions, the absolute difference in 90-day mortality was ...

The results showed that meropenem/vaborbactam was non-inferior to piperacillin/tazobactam with an overall success rate of 98.4% vs 94.0%. Results from the Phase 3 ...

The rate of meropenem decay did not differ significantly between container types (PVC and elastomeric infusion device) for the 4- and 20-mg/mL solutions. There was a significant difference for the ...

The content of this evidence review was up-to-date in November 2019. See summaries of product characteristics (SPCs), British national formulary (BNF), or the Medicines and Healthcare products ...