Scientists have found a way to supercharge the immune system’s T cells by blocking a protein called Ant2, essentially rewiring how these cells generate energy. This metabolic reprogramming makes them ...
The study of metabolism within the tumour microenvironment (TME) is a rapidly evolving field that holds significant ...
Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...
Parkinson’s disease may begin reshaping the body’s chemistry years before the first tremor or stiffness appears. A growing ...
Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer ...
Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...
Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...
Efficacy and safety of immune checkpoint inhibitors in Child-Pugh B and C hepatocellular carcinoma: Impact of treatment line, local therapy and bevacizumab combination. This is an ASCO Meeting ...