Mitochondrial dysfunction is associated with various chronic diseases and cancers, including neurodegenerative diseases and ...
Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...
Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...
New Review Integrates Human, Animal, and Cellular Evidence to Reframe AD as a Triad-Centered Disorder Alzheimer’s disease (AD ...
Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.
NRG5051 is a first-in-class, orally bioavailable and CNS-penetrant next-generation inhibitor of the mitochondrial permeability transition pore (mPTP), acting through a novel undisclosed ...
The Agilent Seahorse XF Mito Tox Assay kit is a powerful tool for identifying drug-induced mitochondrial toxicity by directly measuring mitochondrial oxygen consumption rates (OCR). Mitochondrial ...
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The mitochondrial revolution: This single protein could be the secret to living healthier and longer
Scientists have discovered that boosting the COX7RP protein enhances cellular energy efficiency and significantly extends ...
One of the most consistently reported symptoms of long COVID is the tendency for strenuous exercise to make the condition worse. Not only does long COVID reduce a person’s capacity for exercise but ...
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