Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...
The first healthy volunteers have been dosed in an early clinical trial testing NRG5051, a disease-modifying therapy for ALS ...
Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...
New Review Integrates Human, Animal, and Cellular Evidence to Reframe AD as a Triad-Centered Disorder Alzheimer’s disease (AD ...
Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.
Just a few days after scientists announced we're at a pivotal tipping point in Alzheimer's disease research, a team has made a huge breakthrough, proving for the first time how mitochondrial ...
Mice that have a genetic version of mitochondrial disease can easily be mistaken for much older animals by the time they are nine months old: they have thinning grey hair, osteoporosis, poor hearing, ...
This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...
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