The quest for longevity and vitality has captivated humanity for millennia, but only in recent decades has science begun to unravel the biological mechanisms underlying ageing. Today’s anti-ageing ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged ...

The kidney's proximal tubule reabsorbs water, glucose, ions and other small molecules from the urine and thus maintains the ...

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was ...

Scientists at Duke University found that satellite glial cells can deliver healthy mitochondria to injured sensory neurons, restoring energy, reducing inflammation, and significantly relieving ...

Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...

Transferring mitochondria, or the glial cells that produce them, to mice with nerve damage mitigated pain, suggesting a ...