We can all recognise that feeling of muscle fatigue after taking a brisk walk, cycling, running or playing football. Our ability to engage in physical activity for long periods of time is thanks to ...

This Collection supports and amplifies research related to SDG 3 and SDG 9. Mitochondrial dysfunction has been identified as a hallmark of aging, playing a central role in age-associated decline ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...