In Week 15, there were four games with double-digit spreads, and 44-year-old Philip Rivers helped lead his team to the only cover among those underdogs. He's already a betting spread legend.

NFL Week 16 Results According to Madden 26 The L.A. Rams manage to sweep the Seahawks in another close game. This time, it went to Overtime. L.A. earned the first score on the opening drive when Puka Nacua recorded a 16-yard TD reception.

NFL Week 16 betting spreads, lines, point totals for every game on NFL Week 16 schedule, with odds for favorites and underdogs in each NFL matchup.

NFL Week 16 kicks off on Thursday, as the Seahawks host the Rams. Here are the lines for every Week 16 matchup at DraftKings Sportsbook as of Dec. 21.

Colts quarterback Philip Rivers should face less pressure his second week back in the NFL, as his team plays the 49ers on "Monday Night Football."

One twist in these rankings is that the 49ers could end up playing the Super Bowl in their home stadium, which automatically makes most of their games more attractive. If the 49ers do make it to the Super Bowl,