A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...

Profiling noncoding repetitive RNA sequences improves the sensitivity of liquid biopsy diagnostic tests for early stage cancers. As cancer is most treatable in its early stages, developing diagnostic ...

Smaller noncoding RNA is being used in clinical practice and as knowledge grows of long noncoding RNA, use of it should follow, explained Laura Denby, PhD, Kidney Research UK Senior Fellow, senior ...

Terc-53 functions as a molecular scaffold bringing together Hmmr and Trim25, accelerating Hmmr’s ubiquitination-mediated degradation, which consequently leads to neuroinflammation and cognition ...

Bayer executives were keen to stress to Fierce this summer that the German pharma giant’s appetite for dealmaking hasn’t been curbed by a groupwide restructuring. Its latest cancer-focused ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

A study in mouse models and human tissue, carried out by researchers at the Barcelona Institute of Science and Technology Centre for Genomic Regulation (CRG), has found that the small nuceleolar RNA ...