The FDA is conducting a workshop to discuss the science (lack thereof, really) of Morphine Milligram Equivalents as it applies to the atrocious CDC 2016 Opioid Prescribing Guidelines. Public comments ...

April 5, 2012 — Opioid rotation — switching from one opioid drug or route of administration to another to improve the outcome — is largely to blame for the growing number of unintentional deaths ...

In a letter to the FDA, the American Society of Anesthesiologists has addressed public health concerns associated with the use of equianalgesic opioid conversion tables and has recommended a staged ...

For far too many years, pain researchers and clinicians have relied on the concept of the morphine equivalent daily dosage (MEDD), or some variant of it, as a means of comparing the "relative ...

The audio version of this article is generated by AI-based technology. Mispronunciations can occur. We are working with our partners to continually review and improve the results. In its latest brief ...

Sites of action of opioids for pain relief include the brain (cortex, thalamus, hypothalamus, locus coeruleus, amygdala, and periaqueductal gray matter), spinal cord, and peripheral-nerve membrane.