Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies.

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' channel-plugging mechanism. The findings boost the ...

Two studies by scientists at the University of Chicago have demonstrated a new way to look into the inner workings of cells—in particular, to track the flow of ions inside the many tiny organelles ...

Molecular Devices, at SLAS 2015, launched a homogeneous, no-wash assay to measure ligand- and voltage-gated potassium channel activity. The FLIPR® Potassium Assay Kit uses a novel thallium-sensitive ...

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to ...

Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai, New ...

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.