High-resolution structures of nascent polypeptide chains in complex with the ribosome — the cell’s protein-synthesis machinery — reveal how the ribosome guides protein folding. Ribosomal attachment ...
Protein hydrophobicity is a fundamental driver of protein folding dynamics, underpinning the formation of a central hydrophobic core that stabilises the three-dimensional structure amid an aqueous ...
A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and ...
WEST LAFAYETTE, Ind. — The shared culprit in a slew of diseases — cancers, neurodegenerative diseases, diabetes — is molecules our cells have made incorrectly. Think of them as proteins gone wrong.
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