To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

Undruggable targets typically refer to a class of therapeutic targets that are difficult to target through conventional methods or have not yet been targeted, but are of great clinical significance.

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

Researchers uncover a hidden nanoscale mechanism critical for Met receptor activation, providing a new blueprint for targeted ...

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

Chronic diseases such as type 2 diabetes and inflammatory disorders are a major cause of disease burden and deaths around the world, but their treatment has proven difficult because there may not be ...

From AstraZenecaReviewed by Megan Craig, M.Sc. This article and associated images are based on a poster originally authored by Camilla Ruffilli, Helen Boyd, Kevin Moreau and Noam Zelcer and presented ...

The concept of immunotherapy or boosting the body’s immune system to target tumors was first practically applied in the early ...