Brain cells (magenta) in the reward center of a rat’s brain release dopamine in response to opioids. According to a new study by WashU Medicine researchers, male and female rats with a chronic pain ...

A large review of opioid pain relievers prescribed for acute pain has found these medicines provide only small, short-term ...

While opioids are incredibly powerful pain management tools, they can also be highly addictive. Since 2013, the rate of deaths from an overdose due to synthetic opioids, like fentanyl, has steadily ...

A new meta-analysis of 148 studies estimates that 9.3 percent of patients who receive opioid prescriptions for chronic pain experience "dependence" or "opioid use disorder" (D&OUD). The authors, Kyla ...

The world's largest review of opioid pain relievers prescribed for acute pain found these medicines provide only small, short ...

Low-dose opioid therapy provides stable, long-term symptom control and dose stability for patients with augmented restless legs syndrome.