Restoration of circulation to ischaemic tissue after percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) can, paradoxically, increase infarct size owing to ...

A high neutrophil-to-lymphocyte ratio predicts poor recovery in acute ischaemic stroke, but a higher lymphocyte-to-monocyte ratio is linked to better recovery after reperfusion.

Northwestern University researchers have reported a novel injectable nanomaterial that crossed the blood–brain barrier and ...

Please provide your email address to receive an email when new articles are posted on . Among patients who required interhospital transfer for STEMI, nearly 40% had cath lab activation times of less ...

Alternative model systems to study ischemia-reperfusion are needed to support a wide range of disease-related investigations in the life sciences. Ischemia and reperfusion are relevant to many disease ...

Operators safely shaved a few minutes off heart attack reperfusion times by taking patients straight to culprit lesion percutaneous coronary intervention (PCI) when they arrived at the catheterization ...

Skin wounds from ischemia-reperfusion injuries -- tissue damage caused by blood returning to tissues after a period of oxygen deprivation -- may not heal appropriately in some patients, owing to ...

Under ischemic conditions, the deficiency of oxygenated blood supply to the myocardium makes the energy requirements of the heart impossible to satisfy. Several metabolic alterations derive from ...

The study reveals that nicotinic acid (vitamin B3) significantly protects the liver during ischemia-reperfusion injury by suppressing ferroptosis through improved mitochondrial health. In mouse and ...

Ischemic stroke is a leading cause of death and disability in the Western world. At present, intravenous administration of tissue plasminogen activator within 3 h of symptom onset is the only proven ...

Every year, 500,000 people in the United States have an ST-elevation myocardial infarction. 1 Timely and effective reperfusion with the use of either primary percutaneous coronary intervention (PCI) ...