Chromatin endogenous cleavage (ChEC) uses fusion of a protein of interest to micrococcal nuclease (MNase) to target calcium-dependent cleavage to specific genomic loci in vivo. Here we report the ...

An AI system developed by UK-based company DeepMind has achieved the long-sought-after goal of accurately predicting the shape of proteins from their sequence alone, a key part of understanding how ...

We describe a new computer program, Trilogy, for the automated discovery of sequence-structure patterns in proteins. Trilogy implements a pattern discovery algorithm that begins with an exhaustive ...

As genomics research accelerates, scientists face challenges in identifying functional proteins and understanding biological regulation. Traditional ...