Skeletal muscle can be functionally compromised by genetic myopathies, aging, traumatic injuries and tumor ablation. Under some conditions, such as severe traumatic injuries and volumetric muscle loss ...
“This article illuminates the biology behind EDG-5506, demonstrating that modulation of fast skeletal muscle contraction protects against muscle injury, degeneration and fibrosis in models of DMD,” ...
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
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