Strong, gusty winds will lead to dangerous wind chills, prompting extreme cold warnings and watches for the northern Plains and the Upper Midwest.

Ahead of the winter storm, a pair of low-pressure systems is expected to sweep through the Great Lakes region over the next couple of days, churning up lake effect snow that could total up to 2 feet in some areas through the end of the work week, the National Weather Service said.

Late Saturday night through early Sunday: Several hours of freezing rain and freezing drizzle, which could allow ice to accumulate on trees, power lines, bridges and untreated roads. Sunday: Precipitation may become more mixed, with sleet and cold rain, and possibly a few snowflakes mixed in at times.

The National Weather Service issues a litany of notices before and during inclement weather events. They can be important signals on how to respond.

Over 175 million people face heavy snowfall, power outages, and travel disruption as sub-zero temperatures are forecast.

With many Americans still recovering from multiple blasts of snow and unrelenting freezing temperatures in the nation’s northern tier, a new storm is set to emerge this weekend that could coat roads,