The first and largest dataset of genomic structure variations specific to childhood cancers was published today by scientists from St. Jude Children's Research Hospital and the National Cancer ...

Structural genetic variants include large (>50 base pairs) duplications, inversion, translocations or deletions. Recent advances in long-read sequencing and optical genome mapping, combined with more ...

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

New Delhi: At one time it was believed that DNA mutations were the sole cause for cancer. It is now recognised that cancer is a multifactorial disease influenced by genetics, gene regulation, ...