Learning is something everyone does daily—mastering new skills at work, remembering song lyrics, or following directions to new places. But behind these everyday tasks lies a complex biological ...

In AD, synaptic plasticity, the brain's ability to regulate the strength of synaptic connections between neurons, is significantly disrupted. This worsens over time, reducing cognitive and memory ...

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

Astrocytes use the MEGF10 receptor to prune synapses in the striatum, a process essential for dopamine-driven motor learning.

Synaptic plasticity — the brain’s ability to modify the connections between neurons to support learning — is one of the neural functions profoundly altered in Huntington’s disease, with a direct ...