DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

THUWAL, Saudi Arabia — Scientists have finally captured footage of the microscopic machinery that allows our cells to copy ...

If the engines of DNA replication stay in high gear all the time, they eventually stall or even break down. Fortunately, these engines, which consist of protein complexes, have what could be called ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

Danish researchers believe that everyone should monitor their blood folate levels. They argue that a deficiency in folic acid ...