The completion of mitosis is governed by the dephosphorylation of cyclin-dependent kinase (Cdk) substrates and by the ubiquitination of anaphase-promoting complex (APC) substrates. The order in which ...

Mitosis is the complex process in which duplicated chromosomes are condensed, segregated with the help of the mitotic spindle, and packaged in to daughter cell nuclei. Mitosis occurs in five stages: ...

Abstract: In histopathological image analysis, the detection and count of mitotic cells are important biomarkers for determining the degree and aggressiveness of cancer prognosis. Manual detection of ...

This important study combines microscopy and CRISPR screening to identify factors involved in global chromatin organisation, using centromere clustering as a proxy. The authors present solid evidence ...

It is essential that any new cells produced contain genetic information that is identical to the parent cell.

Bacteria are amongst the simplest of organisms – they are made of single cells. Their cell structure is simpler than the cells of animals, plants and fungi.