Quanta Magazine

After 80 Years, Mathematicians Give Famed ‘Erdős Method’ an Upgrade

Decades ago, Paul Erdős used randomness to illuminate the vast and weird world of networks. Now mathematicians are making his ...
Nature

Making samples one billion times bigger lets simple microscopes pinpoint amino acids

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

AbbVie Receives Positive CHMP Opinion for Upadacitinib (RINVOQ®) for the Treatment of Adults and Adolescents with Non-segmental Vitiligo

If approved, upadacitinib is expected to be the first systemic medication for patients with non-segmental vitiligo, addressing important treatment needs ...

Drug peptides defy shape rules, activating receptors without full spiral form

When many of us think about how drugs work in the body, we may first think about how a drug gets into the body, such as a pill versus an injection. In the Gellman Group at the UW–Madison Department of ...

Toward experiment-guided AlphaFold: Researchers overcome AI tool's single-conformation limitation

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...