Changing just a single base in a specific DNA region of a female mouse embryo led to the development of male reproductive organs. A research team led by Nitzan Gonen at Bar-Ilan University in Israel h ...

One extra letter of DNA. That was all it took to override an entire chromosome’s worth of instructions and turn a female ...

Scientists discovered that making a very small change to female mice's DNA caused them to develop male reproductive organs.

As humankind moves toward establishing a long-term presence on the moon and Mars, the question of whether reproduction is possible in extraterrestrial environments may no longer be merely hypothetical ...

A study published in Cell Research [ advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental ...

A single DNA letter, inserted into a stretch of the genome that doesn’t code for any protein, was enough to turn genetically ...

Some animals can regrow lost body parts. Salamanders and frog tadpoles can rebuild entire limbs after amputation. Mammals ...

Low oxygen levels trigger the early phase of limb regeneration in mammals by stabilizing the protein HIF1A. This promotes rapid wound healing and primes the activation of genes required for ...

Researchers have discovered why amphibians regenerate limbs and mammals do not ...

Researchers have unveiled a new biological platform for studying mitochondrial DNA in physiology, adaptation, disease mechanisms, and therapeutic development.

Using rapid protein degradation, chemogenomics, and super‑resolution microscopy in mouse embryonic stem cells, the team dissected the distinct contributions of BRD2 and BRD4 to transcription.