Intron retention is recognized as a key process in disease development, but its role in tuberculosis (TB) progression is ...

Discusses Topline Results From Lowest Dose MAD Cohort in Phase II FREEDOM2 Study With Favorable Safety, Splicing and vHOT Data March ...

Acute myeloid leukemia (AML) remains one of the most difficult blood cancers to treat. Although drug combinations are often ...

Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global ...

Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global population infected with ...

PepGen Inc. shares plunged about 65% after mixed Phase 2 data for PGN-EDODM1 in DM1, with no functional improvement at 5 ...

A new study from the Italian Institute of Technology (IIT), in collaboration with Uppsala University (Sweden) and AstraZeneca, shows how computational chemistry and supercomputers can help scientists ...

The study focused on splicing, an essential process that enables cells to read genes and function properly, by simulating the functional dynamics of a very large and realistic model system (~2 million ...

Despite many efforts over the years, drug developers have not yet secured an FDA approval for a disease-modifying osteoarthritis drug (DMOAD). Biosplice Therapeutics aims to change that with its ...

Solid tumors are heterogeneous with an immunosuppressive tumor microenvironment, but that is not slowing the search to treat the most difficult, recalcitrant cases ...