Structures called desmosomes connect cells to each other and transfer mechanical stress. They are especially important in tissues under continual mechanical stress, such as heart muscle (pictured).

Dynamic regulation of mitochondrial fission and fusion is crucial for maintaining cellular homeostasis. However, the process regulating mitochondrial fission, especially the constriction step, is ...

How did life leap from simple microbial cells to the complex, structured cells that make up animals, plants, and fungi? A new study in The EMBO Journal by researchers at the Indian Institute of ...

Mechanical forces are transduced to nuclear responses via the linkers of the nucleoskeleton and cytoskeleton (LINC) complex, which couples the cytoskeleton to the nuclear lamina and associated ...

Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122 Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an estrogen independent manner. Targeting vimentin and/or the long ...

A NOVEL autoimmune meningoencephalomyelitis associated with autoantibodies targeting the astrocytic intermediate filament protein vimentin has been identified in a recent case series. This discovery ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Intermediate filaments (IF) are a family of chemically ...

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