The study will assess the tolerability, safety, maximum tolerated dose, and the recommended Phase II dose of PLT012.

Sleep apnea affects nearly one billion people worldwide and causes repeated episodes of oxygen deprivation during the night, ...

Ketogenic diet therapies, including the classic ketogenic diet, modified Atkins diet, and low glycaemic index treatment, have ...

Immunotherapy has revolutionized cancer treatment, yet response rates remain highly variable across tumor types and individual patients. Increasing evidence ...

A new review outlines design principles and applications of synthetic membraneless organelles built through liquid-liquid phase separation for use in biotechnology.

Cancer biology increasingly recognizes that cancer stem cells (CSCs) represent a critical subpopulation within tumors, marked by their self-renewal, ...

The mechanism of action of mRNA vaccines goes far beyond harnessing host cellular machinery to produce antigenic proteins to spur immunity, write Nicolas Hulscher, M.P.H., Peter A. McCullough, M.D., M ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

A new study reports that GLP-1 semaglutide medications may help reverse the effects of osteoarthritis in the joints by ...

Roswell Park Comprehensive Cancer Center postdoctoral researcher Catherine Rono studies how metabolic stress in myeloid cells ...

Scientists at City of Hope, the Broad Institute and Keio University have discovered how specific gut bacteria work together with diet to flip a metabolic switch — transforming energy‑storing white fat ...

Breast cancer patients should avoid fatty foods, warns a new study. Researchers found that a high-fat diet accelerates the ...