Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium ...

Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Visualization, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, and Center ...

Synaptic integrity allows our synapses to "fire and wire" together in ways that optimize neuroplasticity and enhance cognition. Without synaptic integrity, synapses lose their connectivity, which ...

At 15 years old, Sammy considered himself an expert on cannabis. When I asked what he knew about how marijuana interacts with the brain, he confidently explained, “THC activates cannabinoid receptors ...

Communication between neurons relies on highly specialized structures (synapses) where an activated presynaptic neuron releases packets of neurotransmitter molecules that diffuse across a narrow gap ...

Version of Record: This is the final version of the article. - A summary of what the authors were trying to achieve: The authors focused on Rac1, one of the most extensively studied members of the Ras ...

Researchers from the University of Tokyo reveal how the presynaptic Ube3a E3 ligase, a causal factor in Angelman syndrome, eliminates neural chat. The study helps find a better drug target for the ...

The organization of neural circuits determines nervous system function. Variability can arise during neural circuit development (e.g. neurite morphology, axon/dendrite position). To ensure robust ...

A new study has revealed how tau – a microtubule-binding protein that is implicated in Alzheimer’s disease – weakens transmission across synapses in the brains of mice When injected into presynaptic ...

As you’re reading this sentence, the cells in your brain, called neurons, are sending rapid-fire electrical signals between each other, transmitting information. They’re doing so via tiny, specialized ...