In a bid to treat blindness, Life Biosciences will try out potent cellular reprogramming technology on volunteers. When Elon Musk was at Davos last week, an interviewer asked him if he thought aging ...

Et si l’on pouvait transformer n’importe quelle cellule du corps en arme ultra-ciblée contre le cancer ? Des chercheurs viennent de créer un véritable « livre de recettes » moléculaire permettant de ...

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, which are infection and tumor-fighting white blood cells, so that they have a ...

Peut-on modifier notre apprentissage sans chirurgie cérébrale ? Une avancée majeure : les ultrasons ciblent le plaisir et la motivation ! Une équipe de chercheurs, menée par l'Université de Plymouth, ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...

Tricking cancer cells into self-destructing could reduce risk of recurrence and death in colon cancer by 50%. Results also demonstrate the transformative potential of human-based, non-animal research ...

Daylight is one of the most effective tools in architecture. It creates atmosphere, improves comfort, and reduces energy demand. However, integrating daylight successfully requires precision at every ...

State Key Laboratory of Bioactive Molecules and Druggability Assessment, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry ...

Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart disease. However, current reprogramming strategies require excessive factors due to ...

Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to cardiac ...