Abstract: Population structure can be revealed using Single Nucleotide Polymorphisms (SNPs) which are genetic variations found in the DNA sequences of individuals. Due to the large number of SNPs, ...

Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.

BacPhase employs restriction enzyme digestion and PacBio HiFi sequencing to successfully construct bin markers and anchor over 59% of potato genome scaffolds to chromosomes without physical maps, ...

In this issue, Zhai et al. (1) report a “DNA language model” designed to help identify the most critical variants in DNA sequence. With only a four-letter alphabet (A, C, G, and T), most base pairs in ...

BACKGROUND Elite controllers (ECs) are a rare subset of individuals who naturally suppress human immunodeficiency virus type 1 (HIV-1) replication in the absence of antiretroviral therapy. Specific ...

Summary: A new AI tool called RibbonFold is revolutionizing how scientists understand misfolded proteins linked to Alzheimer’s and Parkinson’s. Unlike existing tools such as AlphaFold, which predict ...

Researchers have successfully sequenced the RHCE gene, which could lead to novel diagnostic tools for HDFN. The authors aimed to use next-generation sequencing (NGS) to identify allele-specific ...

† Department of Chemistry, Krieger School of Arts and Sciences, Johns Hopkins University, 3400 N. Charles St., Baltimore, Maryland 21218, United States ‡ Department of Materials Science and ...

The legume Glycine max (soybean) plays an important economic role in the international commodities market, with a world production of almost 260 million tons for the 2009/2010 harvest. The increase in ...

Genomic Laboratory, Department of Animal Biology, Cheikh Anta Diop University, Dakar, Senegal. 2.1. Study Site and Choice of Animals The study was conducted in the Dakar region, where all the Ladoum ...

The brown planthopper (BPH; Nilaparvata lugens) is one of India’s most destructive pests of rice. BPH, a monophagous migratory insect, reported from all major rice-growing ecosystems of the country, ...